亚博取款非常快

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孔杜林教授

亚博取款非常快:

1.导师的个人简介

孔杜林,男,198110月生,博士,教授,海南省南海名家,海南省拔尖人才,海南医亚博取款非常快青年岗位能手。2012.02至现在海南医亚博取款非常快药亚博取款非常快从事教学与科研工作,2014年破格副教授,2017年破格教授。现任药亚博取款非常快有机化学及物理化学教研室副主任,药亚博取款非常快教学工作委员会委员,药亚博取款非常快教学督导组专家,药亚博取款非常快学术骨干,主要从事绿色有机化学和药物合成研究工作,主持和参加国家自然科学基金、海南重点科技计划项目、海南省自然科学基金面上项目、海南省自然科学基金高层次人才等多项课题研究工作,在ACS Sustainable Chemistry & Engineering, Organic & Biomolecular Chemistry, Synthesis等国际权威杂志以第一作者和通讯作者发表SCI收录的学术论文20余篇,其中1top期刊1篇,IF>51篇,IF>27篇,累计影响因子达30以上,参编教材和著作4部。

2.研究方向

药物合成研究

3.发表的学术论文和专著

(一)以第一作者和通讯作者发表的SCI论文:

1Tiao Huang, Li Liu, Qinghe Wang, Dulin Kong*, Mingshu Wu*, P(OEt)3 -Mediated Formal S–H Insertion: Reductive Couplings of Isatins with Thiols to Generate 3-Sulfenylated Oxindoles. Synthesis, 2020, DOI: 10.1055/s-0040-17071

2Tiao Huang, Li Liu, Qinghe Wang, Dulin Kong*, Mingshu Wu*, 1,3-Dipolar Cycloaddition of 3-Amino Oxindole-Based Azomethine Ylides and O-Vinylphosphonylated Salicylaldehydes for Diastereoselective Synthesis of Oxindole Spiro-P,N-polycyclic Heterocycles. Synthesis, 2020, 52(09): 1387-1397

3Xun Chen,* Xue Cui, Lili Bai, Ying Wang, Ying Xie,* Shuojin Wang, Ruirui Zhai, Ke Zhao, Dulin Kong,* and Youbin Li*.Ruthenium(II)-Catalyzed C-H Bond [3+2] Annulation of N-Nitrosoanilines with Alkynes in Water. Asian Journal of Organic Chemistry, 2019, 8(12): 2209-2212

4Dulin Kong, Tiao Huang, Min Liang, Mingshu Wu* and Qiang Lin*. KIO3-catalyzed cross dehydrogenative coupling reaction: sulfenylation of phenol and arylamine derivatives in water at room temperature. Organic & Biomolecular Chemistry, 2019,17(4): 830-834

5Dulin Kong, Qinghe Wang, Tiao Huang, Min Liang, Qiang Lin*, Mingshu Wu*. Metal-free direct regioselective thiolation of imidazoheterocycles in water at room temperature. Tetrahedron, 2019, 75(10): 1457-1463.

6Du-lin Kong, Guo-ping Lu*, Ming-shu Wu, Zai-feng Shi, and Qiang Lin*. One-Pot, Catalyst-Free Synthesis of Spiro[dihydroquinoline naphthofuranone] Compounds from Isatins in Water Triggered by Hydrogen Bonding E?ects. ACS Sustainable Chemistry & Engineering, 2017, 5 (4): 3465–3470

7Dulin Kong, Qinghe Wang, Zhongxiang Zhu, Xianghui Wang, Zaifeng Shi, Qiang Lin*, Mingshu Wu*. Convenient one-pot synthesis of thiobarbituro-quinoline derivatives via catalyst-free multicomponent reactions in water. Tetrahedron Letters, 2017, 58(27): 2644-2647

8Dulin Kong, Zhongxiang Zhu, Jie Jiang, Luyong Wu, Xianghui Wang, Zaifeng Shi, Qiang Lin*, and Mingshu Wu*. A One-Pot, Green Synthesis of Betti Base Containing Adenine Derivatives in Aqueous Medium. Heterocycles, 2017, 94(2): 297-307

9Dulin Kong, Jie Jiang, Qinghe Wang, Zhongxiang Zhu, Xianghui Wang, Luyong Wu, Zaifeng Shi, Mingshu Wu*, Qiang Lin*. Synthesis, Structure and Antimicrobial Activity of 2?-Thioxo-2?,3?-dihydro-1?H,2H- spiro[naphtho[2,1-b]furan-1,5?-pyrimido- [4,5-b]quinoline]-2,4?(10?H)-dione.Chinese Journal of Structural Chemistry, 2017, 36(5): 781-785

10Dulin Kong, Xianghui Wang, Zaifeng Shi, Mingshu Wu, Qiang Lin* and Xin Wang. Solvent- and catalyst-free synthesis of imidazo[1,2-a]pyridines under microwave irradiation. Journal of Chemical Research, 2016, 40(9): 529-531

11Dulin Kong, Jie Jiang, Luyong Wu, Xianghui Wang, Zaifeng Shi, Mingshu Wu, Xin Wang*, Qiang Lin*. Synthesis, Structure and Antimicrobial Activity of 9,9-Dimethyl-9,10-dihydrospiro [benzo[a]- xanthene-12,3?-indoline]-2?,11(8H)- dione. Chinese Journal of Structural Chemistry, 2016, 35(12): 1849-1854

12Zhi-Qiang Cai, Xu Hou, Du-Lin Kong*, Ling Hou and Zhi-Quan Hu. Synthesis,crystal structural, and spectral characterisation of dabigatran etexilate tetrahydrate. Journal of Chemical Research, 2016, 40(8): 461-466

13Dulin Kong, Rendie Liu, Guozhu Li, Pengwei-Zhang* and Mingshu Wu*. A Rapid Convenient, Solventless Green Approach for the Synthesis of a-Hydroxyphosphonates by Grinding. Asian Journal of Chemistry, 2014, 26(4): 1246-1248

14Dulin Kong*, Guozhu Li, Rendie Liu, Synthesis and Crystal Structure of Diethyl Tosyloxybenzylphosphonate. Asian Journal of Chemistry, 2014, 26(7), 2138-2140

15Dulin Kong, Mingshu Wu*, Changri Han, Jingya Ma and Dehui Wan. Synthesis and Characterization of α-aminophosphonic acids Containing Adenine. Asian Journal of Chemistry, 2011, 23(7): 2871-2873

16Dulin Kong, Mingshu Wu*, Huiyan Li and Jingya Ma. 9-(1,1-Dimethyl -3-oxobutyl)adenine. Acta Crystallographica Section E, 2010, E66: o2475- o2475

17孔杜林, 吴明书*, 李倩倩, 马静雅. cis-3-芳脲基-2-苯基-2-氧代萘并[1,2-d]-1,2-氧膦杂环戊烷合成,有机化学,2010, 30(12): 1911-1913

(二)著作:

1.孔杜林(合著,本人撰写约10万字).《染料生产技术》.北京:科学出版社,2014.4

2.孔杜林(合著,本人撰写约12.1万字). 《精细有机中间体生产技术》.北京:科学出版社,2016.4

4.获得的发明专利(标注名次)

获得授权的国家发明专利1项(ZL201910916491.7),排名第四。

5.主持过的科研项目(项目名称;项目编号;级别;经费;起止日期)

1)海南省自然科学基金面上项目(20162033):69-位取代新型嘌呤开环核苷类化合物的合成及抗病毒活性研究2016-012018-12,8万元,主持。

2)海南省自然科学基金高层次人才项目(2019RC215):基于水介质中多组分反应构筑吲哚类抗肿瘤小分子化合物的研究,2020-012022-12,10万元,主持。

3)海南省水环境污染治理与资源化重点实验室课题:水介质中构建靛红螺环化合物的研究,2017-092020-09,3万元,主持。

4海南医亚博取款非常快科研培育基金(HY2015-02):新型嘌呤无环核苷类化合物的合成,2016-012017-12,2.2万元,主持。

5海南医亚博取款非常快教育科研课题(HYP201932):TBLPBL教学法在药学专业有机化学教学中的应用与探索,2019-062021-05,0.5万元,主持。

6.获奖情况

2014年荣获海南医亚博取款非常快临床专业认证先进个人;

2015年指导学生在第八届全国大学生药苑论坛中荣获三等奖;

2017年指导学生在海南省首届高校大学生化学实验技能竞赛中荣获一等奖;

2018年在《结构化学》举办的优秀论文评选活动,荣获优秀奖;

2019年入选海南省南海名家青年项目,海南省拔尖人才;

2019年指导学生荣获海南省第九届挑战杯大学生课外学术科技作品竞赛自然科学类二项三等奖;

2019年指导学生荣获海南医亚博取款非常快互联网+”优秀奖;

2019年荣获海南医亚博取款非常快社会实践优秀指导老师;

2019年荣获海南医亚博取款非常快青年岗位能手称号。

亚博取款非常快-腾讯指南